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Side Effects of Forskolin

Made from the Indian Coleus plant, Forksolin is used to boost levels of cyclic AMP (cAMP), necessary for several important biochemical processes within the human body. Forksolin is typically used for the treatment of various digestive disorders as well as some instances of nausea and intestinal spasms. Forksolin is sometimes used to treat skin burns, insect bites and some allergies. It has also been used to treat neck stiffness and rheumatism, infections, heart conditions and certain blood-related conditions and circulation issues.

Forksolin increases heartbeats in users by affecting the muscles in the heart and blood vessels, resulting in lower blood pressure in patients who need to lower their blood pressure for health reasons. The medication can also be taken by mouth, administered intravenously for heart failure or inhaled in powder form for asthma. Drops are typically used to treat glaucoma. Be aware of the following potential side effects associated with Forksolin:

• When administered by IV, Forksolin may cause low blood pressure or flushing.
• Eye drops may cause a stinging sensation in some patients.
• Throat irritation, tremors, cough or restlessness may occur when inhaled.

Precautions to Consider Before Taking Forksolin

There have not been sufficient studies regarding the safety of Forksolin during pregnancy. However, since high does of Forksolin may be unsafe for expectant mothers, it is recommended to avoid using the drug during pregnancy to err on the side of caution.

There is not sufficient evidence either way to suggest how Forksolin may affect nursing mothers. However, the general recommendation is to err on the side of caution and avoid use while nursing.

Some patients using Forksolin may be at an increased risk of bleeding. It should be noted that such occurrences appear to be rare.

Heart Disease
Forksolin may lower blood pressure. While this is generally a positive effect for patients who need to lower there blood pressure, this could be problematic for individuals with certain heart conditions. This is an especially important precaution for patients undergoing treatments for blood vessel disease or heart disease.

Note: Forskolin not for patients whose blood pressure is already under control or low.

In some cases, Forksolin may increase the risk of bleeding during or after surgery. The general recommendation is that patients using Forksolin should stop taking the drug at least two weeks prior to their scheduled surgery.

*Possible Interactions (Don’t take with these medications)

Severe Interactions
Some medications for high blood pressure may interact with Forksolin, especially calcium channel blockers. Since Forksolin may lower blood pressure, it may interfere with any medications a patient is already taking to lower their blood pressure, possibly resulting in blood pressure that gets too low. Such medications may include:

• Nifedipine (Adalat, Procardia)
• Diltiazem (Cardizem)
• Felodipine (Plendil)

Forskolin also increase blood flow. Patients already taking medications to increase blood flow or circulation to the heart may feel lightheaded or experience dizziness. Medications for blood flow that may be affected by Forskolin include:

• Nitroglycerin
• Isosorbide (Sorbitrate, Imdur, Isordil)

Moderate Interactions
Some patients taking medications to slow clotting may experience mild interactions when also taking Forksolin. Anticoagulant and antiplatelet drugs, in particular, may result in mild interactions, possibly increasing the chances of bleeding or causing patients to bruise easily. Such medications typically include:

• Aspirin
• Ibuprofen (Advil, Motrin)
• Heparin
• Warfarin (Coumadin)

Forksolin is relatively safe when taken properly according to the doctor’s instructions specific to a particular user and monitored by a doctor through regular blood tests and other tests deemed necessary to monitor how Forksolin is working for a particular user. Studies suggest that Forksolin is usually safe for most adults when administered by IV, inhaled, used as a dietary supplement, or applied as drops to the eyes. It is important for anyone taking supplements or similar medications to speak with their doctor first.

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